Why standing-up more could be key to anti-ageing

Study finds sitting down less lengthens telomeres and protects DNA

Spending more time standing up could be key to slowing the anti-aging process and even extending lifespan, a new study has suggested
Spending more time standing up could be key to slowing the anti-aging process and even extending lifespan, a new study has suggested

Spending more time standing up could be key to slowing the ageing process and even extending lifespan, a new study has suggested.

A team at the Karolinska University Hospital in Sweden found reducing the amount of time elderly people spend sitting down protects their DNA.

Researchers said standing up more frequently was associated with longer telomeres, or caps which guard the end of chromosomes and the genetic code inside.

Shorter telomeres are linked to age-related illnesses such as heart disease and some cancers. Previous research has found people who live healthier lifestyles can have longer telomeres.

Lead-author Professor Mai-Lis Hellenius and her team looked at 49 predominantly sedentary and overweight adults, all aged in their late sixties.

Half of them had taken part in a six month exercise programme while the other half were not asked to undertake any physical activity. Physical activity was measured with a diary, questionnaires and a pedometer.

Telomere caps

The team examined telomere lengths from blood tests taken at the beginning of the six months and at the end. They found those who reduced the amount of time spent sitting in the exercise group were associated with telomere lengthening.

Dr Hellenius told Medscape: "We're excited about this study. Long telomeres are linked to a longer, healthier life.

"Our DNA will be damaged during a lifetime. It's damaged by bad diets, smoking, infections, and so on. Our capability to copy and produce new DNA and new cells is so important."

The study, 'Stand up for health—avoiding sedentary behaviour might lengthen your telomeres: secondary outcomes from a physical activity RCT in older people', has been published in the British Journal of Sports Medicine.

Register for free to continue reading

Registration is a free and easy way to support our truly independent journalism

By registering, you will also enjoy limited access to Premium articles, exclusive newsletters, commenting, and virtual events with our leading journalists

Please enter a valid email
Please enter a valid email
Must be at least 6 characters, include an upper and lower case character and a number
Must be at least 6 characters, include an upper and lower case character and a number
Must be at least 6 characters, include an upper and lower case character and a number
Please enter your first name
Special characters aren’t allowed
Please enter a name between 1 and 40 characters
Please enter your last name
Special characters aren’t allowed
Please enter a name between 1 and 40 characters
You must be over 18 years old to register
You must be over 18 years old to register
Opt-out-policy
You can opt-out at any time by signing in to your account to manage your preferences. Each email has a link to unsubscribe.

By clicking ‘Create my account’ you confirm that your data has been entered correctly and you have read and agree to our Terms of use, Cookie policy and Privacy notice.

This site is protected by reCAPTCHA and the Google Privacy policy and Terms of service apply.

Already have an account? sign in

By clicking ‘Register’ you confirm that your data has been entered correctly and you have read and agree to our Terms of use, Cookie policy and Privacy notice.

This site is protected by reCAPTCHA and the Google Privacy policy and Terms of service apply.

Register for free to continue reading

Registration is a free and easy way to support our truly independent journalism

By registering, you will also enjoy limited access to Premium articles, exclusive newsletters, commenting, and virtual events with our leading journalists

Already have an account? sign in

By clicking ‘Register’ you confirm that your data has been entered correctly and you have read and agree to our Terms of use, Cookie policy and Privacy notice.

This site is protected by reCAPTCHA and the Google Privacy policy and Terms of service apply.

Join our new commenting forum

Join thought-provoking conversations, follow other Independent readers and see their replies

Comments

Thank you for registering

Please refresh the page or navigate to another page on the site to be automatically logged inPlease refresh your browser to be logged in